CENP-E combines a slow, processive motor and a flexible coiled coil to produce an essential motile kinetochore tether

The mitotic kinesin centromere protein E (CENP-E) is an essential kinetochore component that directly contributes to the capture and stabilization of spindle microtubules by kinetochores. Although reduction in CENP-E leads to high rates of whole chromosome missegregation, neither its properties as a...

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Detalles Bibliográficos
Autores principales: Kim, Yumi, Heuser, John E., Waterman, Clare M., Cleveland, Don W.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364708/
https://www.ncbi.nlm.nih.gov/pubmed/18443223
http://dx.doi.org/10.1083/jcb.200802189

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364708/
https://www.ncbi.nlm.nih.gov/pubmed/18443223
http://dx.doi.org/10.1083/jcb.200802189

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