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CENP-E combines a slow, processive motor and a flexible coiled coil to produce an essential motile kinetochore tether
The mitotic kinesin centromere protein E (CENP-E) is an essential kinetochore component that directly contributes to the capture and stabilization of spindle microtubules by kinetochores. Although reduction in CENP-E leads to high rates of whole chromosome missegregation, neither its properties as a...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2008
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364708/ https://www.ncbi.nlm.nih.gov/pubmed/18443223 http://dx.doi.org/10.1083/jcb.200802189 |