Oestrogen inhibits resveratrol-induced post-translational modification of p53 and apoptosis in breast cancer cells

Resveratrol, a naturally occurring stilbene, induced apoptosis in human breast cancer MCF-7 cells. The mechanism of this effect was dependent on mitogen-activated protein kinase (MAPK, ERK1/2) activation and was associated with serine phosphorylation and acetylation of p53. Treatment of MCF-7 cells...

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Detalles Bibliográficos
Autores principales: Zhang, S, Cao, H J, Davis, F B, Tang, H-Y, Davis, P J, Lin, H-Y
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2004
Materias:
Experimental Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364738/
https://www.ncbi.nlm.nih.gov/pubmed/15188005
http://dx.doi.org/10.1038/sj.bjc.6601902

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364738/
https://www.ncbi.nlm.nih.gov/pubmed/15188005
http://dx.doi.org/10.1038/sj.bjc.6601902

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