ATM polymorphisms as risk factors for prostate cancer development

The risk of prostate cancer is known to be elevated in carriers of germline mutations in BRCA2, and possibly also in carriers of BRCA1 and CHEK2 mutations. These genes are components of the ATM-dependent DNA damage signalling pathways. To evaluate the hypothesis that variants in ATM itself might be...

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Detalles Bibliográficos
Autores principales: Angèle, S, Falconer, A, Edwards, S M, Dörk, T, Bremer, M, Moullan, N, Chapot, B, Muir, K, Houlston, R, Norman, A R, Bullock, S, Hope, Q, Meitz, J, Dearnaley, D, Dowe, A, Southgate, C, Ardern-Jones, A, Easton, D F, Eeles, R A, Hall, J
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2004
Materias:
Genetics and Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364767/
https://www.ncbi.nlm.nih.gov/pubmed/15280931
http://dx.doi.org/10.1038/sj.bjc.6602007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364767/
https://www.ncbi.nlm.nih.gov/pubmed/15280931
http://dx.doi.org/10.1038/sj.bjc.6602007

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