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A phase I trial of DNA vaccination with a plasmid expressing prostate-specific antigen in patients with hormone-refractory prostate cancer

Prostate-specific antigen (PSA) is a serine protease secreted at low levels by normal luminal epithelial cells of the prostate and in significantly higher levels by prostate cancer cells. Therefore, PSA is a potential target for various immunotherapeutical approaches against prostate cancer. DNA vac...

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Detalles Bibliográficos
Autores principales: Pavlenko, M, Roos, A-K, Lundqvist, A, Palmborg, A, Miller, A M, Ozenci, V, Bergman, B, Egevad, L, Hellström, M, Kiessling, R, Masucci, G, Wersäll, P, Nilsson, S, Pisa, P
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364780/
https://www.ncbi.nlm.nih.gov/pubmed/15280930
http://dx.doi.org/10.1038/sj.bjc.6602019