Synthesis, Structure and Biological Activity of 6-R(3)Si(Ge, Sn)-Substituted 5-Fluorouracils

Direct lithiation of 1-(2-tetrahydrofuryl)-5-fluorouracil (Ftorafur) has been investigated. The treatment of ftorafur with lithium diisopropylamide (LDA)at –70℃ in ether-hexane, followed by the reaction with various electrophiles afforded the corresponding 6-substituted silicon, germanium and tin de...

Descripción completa

Detalles Bibliográficos
Autores principales: Lukevics, E., Ignatovich, L., Shilina, N., Kemme, A., Sjakste, N.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 1994
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364875/
https://www.ncbi.nlm.nih.gov/pubmed/18476217
http://dx.doi.org/10.1155/MBD.1994.65

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364875/
https://www.ncbi.nlm.nih.gov/pubmed/18476217
http://dx.doi.org/10.1155/MBD.1994.65

Ejemplares similares