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Synthesis, Structure and Biological Activity of 6-R(3)Si(Ge, Sn)-Substituted 5-Fluorouracils

Direct lithiation of 1-(2-tetrahydrofuryl)-5-fluorouracil (Ftorafur) has been investigated. The treatment of ftorafur with lithium diisopropylamide (LDA)at –70℃ in ether-hexane, followed by the reaction with various electrophiles afforded the corresponding 6-substituted silicon, germanium and tin de...

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Detalles Bibliográficos
Autores principales:	Lukevics, E., Ignatovich, L., Shilina, N., Kemme, A., Sjakste, N.
Formato:	Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 1994
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364875/ https://www.ncbi.nlm.nih.gov/pubmed/18476217 http://dx.doi.org/10.1155/MBD.1994.65

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