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Monofunctional and Interstrand DNA Adducts of Platinum(II) Complexes

The effects produced in DNA by monofunctional or interstrand adducts of platinum(II) complexes have been summarized. The monofunctional adducts destabilize DNA in a sequence-dependent manner via conformational distortions, which may have a denaturational character. It has been suggested that this co...

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Detalles Bibliográficos
Autores principales: Brabec, Viktor, Boudny, Vladimír
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 1994
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364885/
https://www.ncbi.nlm.nih.gov/pubmed/18476231
http://dx.doi.org/10.1155/MBD.1994.195