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Monofunctional and Interstrand DNA Adducts of Platinum(II) Complexes
The effects produced in DNA by monofunctional or interstrand adducts of platinum(II) complexes have been summarized. The monofunctional adducts destabilize DNA in a sequence-dependent manner via conformational distortions, which may have a denaturational character. It has been suggested that this co...
Autores principales: | Brabec, Viktor, Boudny, Vladimír |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
1994
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364885/ https://www.ncbi.nlm.nih.gov/pubmed/18476231 http://dx.doi.org/10.1155/MBD.1994.195 |
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