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Synthesis of 4-Amino-1-Hydroxy-Butane-1,1-Diphosphonate (AHBDP) - Stannous Complexes for the Preparation of Ahbdp-Sn(II)-Tc and its Biodistribution in Rats
The new potential tracer of bone imaging, AHBDP-Sn(II)-TcO.3H(2)O was synthesized by reducing the TcO(4)(−) to TcO(2)(+) in the presence of AHBDP and Sn(ll)’s reducing agent. We found that tin rapidly forms a stable complex with AHBDP, giving AHBDP-Sn(II).3H(2)O. In the excess of AHBDP-Sn(ll).3H(2)O...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
1995
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364975/ https://www.ncbi.nlm.nih.gov/pubmed/18472767 http://dx.doi.org/10.1155/MBD.1995.201 |