Synthesis of 4-Amino-1-Hydroxy-Butane-1,1-Diphosphonate (AHBDP) - Stannous Complexes for the Preparation of Ahbdp-Sn(II)-Tc and its Biodistribution in Rats

The new potential tracer of bone imaging, AHBDP-Sn(II)-TcO.3H(2)O was synthesized by reducing the TcO(4)(−) to TcO(2)(+) in the presence of AHBDP and Sn(ll)’s reducing agent. We found that tin rapidly forms a stable complex with AHBDP, giving AHBDP-Sn(II).3H(2)O. In the excess of AHBDP-Sn(ll).3H(2)O...

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Detalles Bibliográficos
Autores principales: Mankhetkorn, Samlee, Blanchot, Caroline, Duran-Cordobes, Muriel, El Manouni, Driss, Leroux, Yves, Moretti, Jean-Luc
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 1995
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364975/
https://www.ncbi.nlm.nih.gov/pubmed/18472767
http://dx.doi.org/10.1155/MBD.1995.201

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