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Determination of Biotransformation Products of Platinum Drugs in Rat and Human Urine

Cisplatin is an extremely effective cancer chemotherapeutic agent, but its use is often accompanied by toxicity. Second generation drugs such as carboplatin are becoming more widely used because of reduced toxicity. Since biotransformation products have been implicated in the toxic responses, we hav...

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Detalles Bibliográficos
Autores principales: Tang, Xia, Hayes, II, Jerry W., Schroder, Louis, Cacini, William, Dorsey, John, Elder, R. C., Tepperman, Katherine
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 1997
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2365043/
https://www.ncbi.nlm.nih.gov/pubmed/18475775
http://dx.doi.org/10.1155/MBD.1997.97