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The Development of Novel Organotin Anti-Tumor Drugs: Structure and Activity

An overview of the development of anti-tumor organotin derivatives in selected classes of compounds is presented and discussed. High to very high in vitro activity has been found, sometimes equaling that of doxorubicin. Solubility in water is an important issue, dominating the in vivo testing of com...

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Detalles Bibliográficos
Autores principales: de Vos, Dick, Willem, Rudolph, Gielen, Marcel, van Wingerden, Kyra E., Nooter, Kees
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 1998
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2365118/
https://www.ncbi.nlm.nih.gov/pubmed/18475842
http://dx.doi.org/10.1155/MBD.1998.179