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The Development of Novel Organotin Anti-Tumor Drugs: Structure and Activity
An overview of the development of anti-tumor organotin derivatives in selected classes of compounds is presented and discussed. High to very high in vitro activity has been found, sometimes equaling that of doxorubicin. Solubility in water is an important issue, dominating the in vivo testing of com...
Autores principales: | de Vos, Dick, Willem, Rudolph, Gielen, Marcel, van Wingerden, Kyra E., Nooter, Kees |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
1998
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2365118/ https://www.ncbi.nlm.nih.gov/pubmed/18475842 http://dx.doi.org/10.1155/MBD.1998.179 |
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