Cargando…

Steric Determinants of Pt/DNA Interactions and Anticancer Activity

Studies directed at establishing the structural features that control Pt/DNA interactions and the anticancer activity of Pt drugs are described. [(1)H, (15)N]-HSQC 2D NMR spectroscopic studies of the reactions of cisplatin with oligonucleotides containing ApG and GpA binding sites reveal dramatic di...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hambley, Trevor W., Berners-Price, Susan J., Davies, Murray S., Diakos, Connie I., Er, Hui Meng, Fenton, Ronald R., Ling, Edwina C. H., Rezler, Evonne M.
Formato:	Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 1998
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2365127/ https://www.ncbi.nlm.nih.gov/pubmed/18475844 http://dx.doi.org/10.1155/MBD.1998.197

Ejemplares similares

Steric Hindrance of NH(3) Diffusion on Pt(111) by Co-Adsorbed O-Atoms
por: Borodin, Dmitriy, et al.
Publicado: (2022)

C−X Bond Activation by Palladium: Steric Shielding versus Steric Attraction
por: Hansen, Thomas, et al.
Publicado: (2022)

Characterization of the G-quadruplexes in the duplex nuclease hypersensitive element of the PDGF-A promoter and modulation of PDGF-A promoter activity by TMPyP4
por: Qin, Yong, et al.
Publicado: (2007)

Steric exclusion and protein conformation determine the localization of plasma membrane transporters
por: Bianchi, Frans, et al.
Publicado: (2018)

Determining the Effective Density and Stabilizer Layer Thickness of Sterically Stabilized Nanoparticles
por: Akpinar, Bernice, et al.
Publicado: (2016)

SEROLOGICAL DIFFERENTIATION OF STERIC ISOMERS
por: Landsteiner, K., et al.
Publicado: (1928)

Steric “attraction”: not by dispersion alone
por: Gryn’ova, Ganna, et al.
Publicado: (2018)

Anticancer activity of a Gold(I) phosphine thioredoxin reductase inhibitor in multiple myeloma
por: Sze, Jun Hui, et al.
Publicado: (2019)

Pyrenebutyrate Pt(IV) Complexes with Nanomolar Anticancer Activity
por: Ahmedova, Anife, et al.
Publicado: (2023)

Quelling Inflammation with Ketosis and Steric Chemistry
por: Gleeson, Michael W, et al.
Publicado: (2016)

Steric and electronic control of an ultrafast isomerization
por: Porter, Tyler M., et al.
Publicado: (2019)

Quantifying the role of steric constraints in nucleosome positioning
por: Rube, H. Tomas, et al.
Publicado: (2014)

Ferrocene-Containing Sterically Hindered Phosphonium Salts
por: Ermolaev, Vadim, et al.
Publicado: (2018)

Steric Interference in Bilayer Graphene with Point Dislocations
por: Arca, Francisco, et al.
Publicado: (2019)

Crystal structures of three sterically congested disilanes
por: Pichaandi, Kothanda Rama, et al.
Publicado: (2017)

Sterically Controlled C−H Olefination of Heteroarenes
por: Chen, Hao, et al.
Publicado: (2020)

Non‐Planar Structures of Sterically Overcrowded Trialkylamines
por: Banert, Klaus, et al.
Publicado: (2020)

Ruthenium complexes of sterically-hindered pentaarylcyclopentadienyl ligands
por: Asato, Ryosuke, et al.
Publicado: (2021)

Aglycone sterics-selective enzymatic glycan remodeling
por: Mao, Anwen, et al.
Publicado: (2022)

Note from the President
por: Berners-Price, Sue
Publicado: (2020)

Sterically Demanding Ag(I) and Cu(I) N‐Heterocyclic Carbene Complexes: Synthesis, Structures, Steric Parameters, and Catalytic Activity
por: Cervantes‐Reyes, Alejandro, et al.
Publicado: (2020)

Hydrogen‐Bond Strength of CC and GG Pairs Determined by Steric Repulsion: Electrostatics and Charge Transfer Overruled
por: van der Lubbe, Stephanie C. C., et al.
Publicado: (2017)

London Dispersion Interactions Rather than Steric Hindrance Determine the Enantioselectivity of the Corey–Bakshi–Shibata Reduction
por: Eschmann, Christian, et al.
Publicado: (2021)

Molecular Modeling of Inorganic Compounds
por: Comba, Peter, et al.
Publicado: (2009)

Internal climate variability and projected future regional steric and dynamic sea level rise
por: Hu, Aixue, et al.
Publicado: (2018)

Intracellular trafficking as a determinant of AS-DACA cytotoxicity in rhabdomyosarcoma cells
por: Wolf, Steven J, et al.
Publicado: (2011)

Thermodynamic Evaluation of the Interactions between Anticancer Pt(II) Complexes and Model Proteins
por: Pelosi, Chiara, et al.
Publicado: (2021)

DFT Study on the Substituent Effect of Anticancer Picoline-Diazido-Pt(IV) Compounds
por: Mu, Meilin, et al.
Publicado: (2022)

Impact of Hydrophobic Chains in Five-Coordinate Glucoconjugate Pt(II) Anticancer Agents
por: Annunziata, Alfonso, et al.
Publicado: (2023)

Synthesis and Characterisation of Fluorescent Novel Pt(II) Cyclometallated Complexes with Anticancer Activity
por: McGhie, Brondwyn S., et al.
Publicado: (2023)

Enhanced clickability of doubly sterically-hindered aryl azides
por: Yoshida, Suguru, et al.
Publicado: (2011)

Flow carbonylation of sterically hindered ortho-substituted iodoarenes
por: Mallia, Carl J, et al.
Publicado: (2016)

Protein stabilization by tuning the steric restraint at the reverse turn
por: Lahiri, Priyanka, et al.
Publicado: (2018)

Adaptive responses of sterically confined intramolecular chalcogen bonds
por: Selvakumar, Karuthapandi, et al.
Publicado: (2018)

Steric and Stereochemical Modulation in Pyridyl- and Quinolyl-Containing Ligands
por: Dai, Zhaohua
Publicado: (2016)

Investigating the Influence of Steric Hindrance on Selective Anion Transport
por: Jowett, Laura A., et al.
Publicado: (2019)

Cell penetrating peptide conjugates of steric block oligonucleotides()
por: Lebleu, Bernard, et al.
Publicado: (2008)

Stacking Control by Molecular Symmetry of Sterically Protected Phthalocyanines
por: Kudo, Ryota, et al.
Publicado: (2020)

Metagenomic ene-reductases for the bioreduction of sterically challenging enones
por: Dobrijevic, Dragana, et al.
Publicado: (2019)

The curious case of a sterically crowded Stenhouse salt
por: Théry, Valentin, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_dq3la9osk0m93ict316b4mul3a