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Chemistry and Pharmacokinetics of Gallium Maltolate, a Compound With High Oral Gallium Bioavailability

Gallium maltolate, tris(3-hydroxy-2-methyl-4H-pyran-4-onato)gallium (GaM), is an orally active gallium compound for therapeutic use. It is moderately soluble in water (10.7 ± 0.9 mg/mL at 25∘C) with an octanol partition coefficient of 0.41±0.08. The molecule is electrically neutral in aqueous soluti...

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Detalles Bibliográficos
Autores principales: Bernstein, Lawrence R., Tanner, Trevor, Godfrey, Claire, Noll, Bruce
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2365198/
https://www.ncbi.nlm.nih.gov/pubmed/18475921
http://dx.doi.org/10.1155/MBD.2000.33