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Development of Acid-Sensitive Platinum(II) Complexes With Protein-Binding Properties

Four new protein-binding platinum(II) complexes, 10, 11, 21, 22, in which the dichloroplatinum moiety is coordinated either to a carbon-substituted or a nitrogen-substituted ethylene diamino ligand, were prepared in ten-step syntheses. According to pH-dependent stability studies with strictly relate...

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Detalles Bibliográficos
Autores principales: Schütte, M. T., Mülhaupt, R., Kratz, F.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2365202/
https://www.ncbi.nlm.nih.gov/pubmed/18475930
http://dx.doi.org/10.1155/MBD.2000.89