Cytotoxic Activity of Silyl- and Germyl-Substituted 4,4-Dioxo-3a,6a-Dihydrothieno[2,3−d]isoxazolines-2

The [2+3] dipolar cycloaddition of nitrile oxides to the double C = C bonds of thiophene-1, 1-dioxides leads to formation of the fused isoxazolines-2 (1, 2). Tumor growth inhibition of these compounds strongly depends on the nature of group IV A element increasing from slightly active tert-butyl der...

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Detalles Bibliográficos
Autores principales: Lukevics, E., Arsenyan, P., Shestakova, I., Zharkova, O., Kanepe, I., Mezapuke, R., Pudova, O.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2000
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2365205/
https://www.ncbi.nlm.nih.gov/pubmed/18475927
http://dx.doi.org/10.1155/MBD.2000.63

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2365205/
https://www.ncbi.nlm.nih.gov/pubmed/18475927
http://dx.doi.org/10.1155/MBD.2000.63

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