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High In-Vitro Antitumour Activity of Triphenyltin Coumarin 3-Carboxylate and its Coordination Complexes With Monodentate Oxygen Donor Ligands Against the Epstein Barr Virus (EBV)-DNA Positive Raji and the P-388 Murine Leukaemia Cell Lines, and Evidence for the Suppression by Organotin of the Early Antigen Complex in the EBV Lytic Cycle

Triphenyltin coumarin-3-carboxylate and its coordination complexes with ethanol, triphenylphosphine oxide, triphenylarsine oxide, diphenylcyclopropenone and quinoline N-oxide exhibited high in vitro cytotoxicity (LC(50) values in the range 0.25-3.4 μg/mL) when tested against EBV-DNA positive Raji ce...

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Detalles Bibliográficos
Autores principales: Koshy, Joyce, Das, V. G. Kumar, Balabaskaran, S., Ng, S. W., Wahab, Norhanom
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2365233/
https://www.ncbi.nlm.nih.gov/pubmed/18475952
http://dx.doi.org/10.1155/MBD.2000.245