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Oligonucleotides Modified With Transplatin Derivatives: Fast and Efficient Metalloribozymes

When an oligonucleotide containing a 1,3-(G,G)-transplatin cross-link at a GNG site (N represents a C, T, A or U residue) is paired with its complementary strand, the intrastrand adduct rearranges into an interstrand cross-link, resulting in the covalent attachment of both strands. Here, we have stu...

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Detalles Bibliográficos
Autores principales: Dalbiès-Tran, Rozenn, Leng, Marc, Boudvillain, Marc
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2365245/
https://www.ncbi.nlm.nih.gov/pubmed/18475974
http://dx.doi.org/10.1155/MBD.2001.39