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Oligonucleotides Modified With Transplatin Derivatives: Fast and Efficient Metalloribozymes
When an oligonucleotide containing a 1,3-(G,G)-transplatin cross-link at a GNG site (N represents a C, T, A or U residue) is paired with its complementary strand, the intrastrand adduct rearranges into an interstrand cross-link, resulting in the covalent attachment of both strands. Here, we have stu...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Hindawi Publishing Corporation
2001
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2365245/ https://www.ncbi.nlm.nih.gov/pubmed/18475974 http://dx.doi.org/10.1155/MBD.2001.39 |