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Tumour necrosis factor-α mediates blood—brain barrier damage in HIV-1 infection of the central nervous system

The pathogenesis of brain inflammation and damage by human immunodeficiency virus (HIV) infection is unclear. Because blood–brain barrier damage and impaired cerebral perfusion are common features of HIV-1 infection, we evaluated the role of tumour necrosis factor-α (TNF-α) and interleukin-1β (IL-1β...

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Detalles Bibliográficos
Autores principales: Sharief, M. K., Ciardi, M., Thompson, E. J., Sorice, F., Rossi, F., Vullo, V., Cirelli, A.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 1992
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2365337/
https://www.ncbi.nlm.nih.gov/pubmed/18475460
http://dx.doi.org/10.1155/S0962935192000292