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A PAF receptor antagonist inhibits acute airway inflammation and late-phase responses but not chronic airway inflammation and hyperresponsiveness in a primate model of asthma

We have examined the effects of a PAF receptor antagonist, WEB 2170, on several indices of acute and chronic airway inflammation and associated changes in lung function in a primate model of allergic asthma. A single oral administration WEB 2170 provided dose related inhibition of the release of leu...

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Detalles Bibliográficos
Autores principales: Gundel, R. H., Wegner, C. D., Heuer, H. O., Letts, L. G.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 1992
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2365364/
https://www.ncbi.nlm.nih.gov/pubmed/18475488
http://dx.doi.org/10.1155/S0962935192000577