Cargando…

A PAF receptor antagonist inhibits acute airway inflammation and late-phase responses but not chronic airway inflammation and hyperresponsiveness in a primate model of asthma

We have examined the effects of a PAF receptor antagonist, WEB 2170, on several indices of acute and chronic airway inflammation and associated changes in lung function in a primate model of allergic asthma. A single oral administration WEB 2170 provided dose related inhibition of the release of leu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gundel, R. H., Wegner, C. D., Heuer, H. O., Letts, L. G.
Formato:	Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 1992
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2365364/ https://www.ncbi.nlm.nih.gov/pubmed/18475488 http://dx.doi.org/10.1155/S0962935192000577

Ejemplares similares

Is platelet activating factor (PAF) an important mediator in bronchial asthma?
por: Gundel, R. H., et al.
Publicado: (1992)

The administration of clopidogrel attenuates airway hyperresponsiveness and airway inflammation in an ovalbumin specific allergic asthma model
por: Trinh, Hoang Kim Tu, et al.
Publicado: (2015)

Concomitant Exposure to Ovalbumin and Endotoxin Augments Airway Inflammation but Not Airway Hyperresponsiveness in a Murine Model of Asthma
por: Mac Sharry, John, et al.
Publicado: (2014)

Dissociation by steroids of eosinophilic inflammation from airway hyperresponsiveness in murine airways
por: Birrell, Mark A, et al.
Publicado: (2003)

P2Y12 antagonist attenuates eosinophilic inflammation and airway hyperresponsiveness in a mouse model of asthma
por: Suh, Dong‐Hyeon, et al.
Publicado: (2015)

Immunomodulatory Effects of Ambroxol on Airway Hyperresponsiveness and Inflammation
por: Takeda, Katsuyuki, et al.
Publicado: (2016)

Stigmasterol alleviates allergic airway inflammation and airway hyperresponsiveness in asthma mice through inhibiting substance-P receptor
por: Zhang, Jimei, et al.
Publicado: (2023)

Rosmarinic Acid Attenuates Airway Inflammation and Hyperresponsiveness in a Murine Model of Asthma
por: Liang, Zhengmin, et al.
Publicado: (2016)

Development of Eosinophilic Airway Inflammation and Airway Hyperresponsiveness in Mast Cell–deficient Mice
por: Takeda, K., et al.
Publicado: (1997)

Zinc supplementation alters airway inflammation and airway hyperresponsiveness to a common allergen
por: Morgan, Carrie I, et al.
Publicado: (2011)

Airway hyperresponsiveness is associated with airway remodeling but not inflammation in aging Cav1(-/-) mice
por: Gabehart, Kelsa E, et al.
Publicado: (2013)

Attenuation of allergic airway inflammation and hyperresponsiveness in a murine model of asthma by silver nanoparticles
por: Park, Hee Sun, et al.
Publicado: (2010)

G Protein βγ-Subunit Signaling Mediates Airway Hyperresponsiveness and Inflammation in Allergic Asthma
por: Nino, Gustavo, et al.
Publicado: (2012)

Bronchial hyperresponsiveness to mannitol, airway inflammation and Asthma Control Test in atopic asthmatic children
por: Attanasi, Marina, et al.
Publicado: (2016)

Inhibition of γ-glutamyl transferase suppresses airway hyperresponsiveness and airway inflammation in a mouse model of steroid resistant asthma exacerbation
por: Zhang, Cancan, et al.
Publicado: (2023)

Lignosus rhinocerotis Cooke Ryvarden ameliorates airway inflammation, mucus hypersecretion and airway hyperresponsiveness in a murine model of asthma
por: Johnathan, Malagobadan, et al.
Publicado: (2021)

Eosinophilic Airway Inflammation and Airway Hyperresponsiveness According to Aeroallergen Sensitization Pattern in Patients With Lower Airway Symptoms
por: Jo, Eun-Jung, et al.
Publicado: (2014)

Nociceptin/Orphanin Fq in inflammation and remodeling of the small airways in experimental model of airway hyperresponsiveness
por: Tartaglione, Gioia, et al.
Publicado: (2018)

Tanshinone IIA attenuates ovalbumin-induced airway inflammation and hyperresponsiveness in a murine model of asthma
por: Wang, Shi-Biao, et al.
Publicado: (2019)

Obesity Induced by Neonatal Overfeeding Worsens Airway Hyperresponsiveness and Inflammation
por: Ye, Zehui, et al.
Publicado: (2012)

Does Airway T2 Inflammation Increase the Severity of Bronchial Hyperresponsiveness?
por: Jiménez-Gómez, Miguel, et al.
Publicado: (2023)

Airway resistance at maximum inhalation as a marker of asthma and airway hyperresponsiveness
por: Mendonça, Nancy T, et al.
Publicado: (2011)

IRAK-M knockout promotes allergic airway inflammation, but not airway hyperresponsiveness, in house dust mite-induced experimental asthma model
por: Zhang, Xudong, et al.
Publicado: (2021)

The MIF Antagonist ISO-1 Attenuates Corticosteroid-Insensitive Inflammation and Airways Hyperresponsiveness in an Ozone-Induced Model of COPD
por: Russell, Kirsty E., et al.
Publicado: (2016)

Asthmatic Airway Inflammation is More Closely Related to Airway Hyperresponsiveness to Hypertonic Saline than to Methacholine
por: Choi, Inseon S., et al.
Publicado: (2003)

Additive Effect of Diesel Exhaust Particulates and Ozone on Airway Hyperresponsiveness and Inflammation in a Mouse Model of Asthma
por: Jang, An-Soo, et al.
Publicado: (2005)

Tomatidine Attenuates Airway Hyperresponsiveness and Inflammation by Suppressing Th2 Cytokines in a Mouse Model of Asthma
por: Kuo, Chieh-Ying, et al.
Publicado: (2017)

Interleukin 33 exacerbates antigen driven airway hyperresponsiveness, inflammation and remodeling in a mouse model of asthma
por: Sjöberg, L. C., et al.
Publicado: (2017)

Ruxolitinib Ameliorates Airway Hyperresponsiveness and Lung Inflammation in a Corticosteroid-Resistant Murine Model of Severe Asthma
por: Subramanian, Hariharan, et al.
Publicado: (2021)

Vaccination against IL-33 Inhibits Airway Hyperresponsiveness and Inflammation in a House Dust Mite Model of Asthma
por: Lei, Ying, et al.
Publicado: (2015)

Hypoargininemia exacerbates airway hyperresponsiveness in a mouse model of asthma
por: Cloots, Roy H. E., et al.
Publicado: (2018)

Chlamydophila pneumoniae induces a sustained airway hyperresponsiveness and inflammation in mice
por: Blasi, Francesco, et al.
Publicado: (2007)

Eosinophil Inflammation and Hyperresponsiveness in the Airways as Phenotypes of COPD, and Usefulness of Inhaled Glucocorticosteroids
por: Kume, Hiroaki, et al.
Publicado: (2019)

The role of measuring airway hyperresponsiveness and inflammatory biomarkers in asthma
por: Currie, Graeme P, et al.
Publicado: (2005)

Airway Hyperresponsiveness in Asthma: Mechanisms, Clinical Significance, and Treatment
por: Brannan, John D., et al.
Publicado: (2012)

Small Airway Impairment and Bronchial Hyperresponsiveness in Asthma Onset
por: Sposato, Bruno, et al.
Publicado: (2014)

Exposure to urban PM1 in rats: development of bronchial inflammation and airway hyperresponsiveness
por: Filep, Ágnes, et al.
Publicado: (2016)

Contribution of Nitric Oxide Synthases 1, 2, and 3 to Airway Hyperresponsiveness and Inflammation in a Murine Model of Asthma
por: De Sanctis, George T., et al.
Publicado: (1999)

Ganoderma formosanum polysaccharides attenuate Th2 inflammation and airway hyperresponsiveness in a murine model of allergic asthma
por: Pi, Chia-Chen, et al.
Publicado: (2014)

Trigger of bronchial hyperresponsiveness development may not always need eosinophilic airway inflammation in very early stage of asthma
por: Obase, Yasushi, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_1c1dvt8fd72dc7r29a4vvkebeg