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Inhibition of smooth muscle contraction and platelet aggregation by peptide 204–212 of lipocortin 5: an attempt to define some structure requirements

Peptide 204–212 of lipocortin (LC) 5 inhibited porcine pancreatic phospholipase A(2) (PLA(2)) induced rat stomach strip contractions and ADP induced rabbit platelet aggregation in a concentration dependent manner (IC(30) of 10 μM and 400 μM, respectively). The first two amino acids are not necessary...

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Detalles Bibliográficos
Autores principales: Mugridge, K. G., Becherucci, C., Parente, L., Perretti, M.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 1993
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2365395/
https://www.ncbi.nlm.nih.gov/pubmed/18475510
http://dx.doi.org/10.1155/S0962935193000146