Combined Inactivation of MYC and K-Ras Oncogenes Reverses Tumorigenesis in Lung Adenocarcinomas and Lymphomas

BACKGROUND: Conditional transgenic models have established that tumors require sustained oncogene activation for tumor maintenance, exhibiting the phenomenon known as “oncogene-addiction.” However, most cancers are caused by multiple genetic events making it difficult to determine which oncogenes or...

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Detalles Bibliográficos
Autores principales: Tran, Phuoc T., Fan, Alice C., Bendapudi, Pavan K., Koh, Shan, Komatsubara, Kim, Chen, Joy, Horng, George, Bellovin, David I., Giuriato, Sylvie, Wang, Craig S., Whitsett, Jeffrey A., Felsher, Dean W.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2365560/
https://www.ncbi.nlm.nih.gov/pubmed/18461184
http://dx.doi.org/10.1371/journal.pone.0002125

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2365560/
https://www.ncbi.nlm.nih.gov/pubmed/18461184
http://dx.doi.org/10.1371/journal.pone.0002125

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