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Role of transforming growth factor-β(1) in down-regulating TNF production by alveolar macrophages during asbestos-induced pulmonary fibrosis

Activation of alveolar macrophages (AM) for tumour necrosis factor production is suppressed initially during the inflammatory response to fibrogenic dusts. We investigated the mechanisms involved in TNF suppression, notably the role of other AM-derived mediators including prostaglandin E(2) (PGE(2))...

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Detalles Bibliográficos
Autores principales: Lemaire, Irma, Ouellet, Sophie
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 1996
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2365768/
https://www.ncbi.nlm.nih.gov/pubmed/18475695
http://dx.doi.org/10.1155/S0962935196000063