Dimeric and polymeric IgA, but not monomeric IgA, enhance the production of IL-6 by human renal mesangial cells

Depositions of IgA in the renal glomerular mesangial area are a hallmark of IgA nephropathy, and are thought to be crucial for the onset of inflammation processes in IgA nephropathy. In this report we show that human mesangial cells (MC) in vitro bind IgA and that binding of IgA enhances the product...

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Detalles Bibliográficos
Autores principales: Reterink, T. J. F., Schroeijers, W. E. M., Es, L. A. van, Daha, M. R.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 1996
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2365790/
https://www.ncbi.nlm.nih.gov/pubmed/18475715
http://dx.doi.org/10.1155/S0962935196000269

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2365790/
https://www.ncbi.nlm.nih.gov/pubmed/18475715
http://dx.doi.org/10.1155/S0962935196000269

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