Cargando…

Folding and assembly of large macromolecular complexes monitored by hydrogen-deuterium exchange and mass spectrometry

Recent advances in protein mass spectrometry (MS) have enabled determinations of hydrogen deuterium exchange (HDX) in large macromolecular complexes. HDX-MS became a valuable tool to follow protein folding, assembly and aggregation. The methodology has a wide range of applications in biotechnology r...

Descripción completa

Detalles Bibliográficos
Autores principales: Suchanova, Bohumila, Tuma, Roman
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2365927/
https://www.ncbi.nlm.nih.gov/pubmed/18394161
http://dx.doi.org/10.1186/1475-2859-7-12