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Folding and assembly of large macromolecular complexes monitored by hydrogen-deuterium exchange and mass spectrometry
Recent advances in protein mass spectrometry (MS) have enabled determinations of hydrogen deuterium exchange (HDX) in large macromolecular complexes. HDX-MS became a valuable tool to follow protein folding, assembly and aggregation. The methodology has a wide range of applications in biotechnology r...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2008
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2365927/ https://www.ncbi.nlm.nih.gov/pubmed/18394161 http://dx.doi.org/10.1186/1475-2859-7-12 |