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Antioxidant and Prooxidant Effects of Metal Dafonates on the NADPH-Dependent Lipid Peroxidation in the Murine Hepatic Microsomal System

Dafone inhibits the lipid peroxidation significantly in a concentration dependent manner. The inhibition was found to be an uncompetitive type with the inhibition constant (Ki) of 62.5μM On the other hand complexation with metal ions results in a significant reversal from antioxidant to pro-oxidant...

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Detalles Bibliográficos
Autores principales: Gupta, M., Kale, R. K., Kulkarni, P. P., Padhye, S. B.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2366826/
https://www.ncbi.nlm.nih.gov/pubmed/18472908
http://dx.doi.org/10.1155/MBD.1999.169