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Antioxidant and Prooxidant Effects of Metal Dafonates on the NADPH-Dependent Lipid Peroxidation in the Murine Hepatic Microsomal System
Dafone inhibits the lipid peroxidation significantly in a concentration dependent manner. The inhibition was found to be an uncompetitive type with the inhibition constant (Ki) of 62.5μM On the other hand complexation with metal ions results in a significant reversal from antioxidant to pro-oxidant...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Hindawi Publishing Corporation
1999
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2366826/ https://www.ncbi.nlm.nih.gov/pubmed/18472908 http://dx.doi.org/10.1155/MBD.1999.169 |