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A likelihood-based procedure for obtaining confidence intervals of disease loci with general pedigree data

We proposed a confidence interval method for disease gene localization by testing every position on each chromosome of interest for its possibility of being a disease locus and including those not rejected into the interval. Three test statistics were proposed to perform the tests, including one bas...

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Detalles Bibliográficos
Autores principales: Wan, Shuyan, Lin, Shili
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2367465/
https://www.ncbi.nlm.nih.gov/pubmed/18466446