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Joint modeling of linkage and association using affected sib-pair data

There has been a growing interest in developing strategies for identifying single-nucleotide polymorphisms (SNPs) that explain a linkage signal by joint modeling of linkage and association. We compare several existing methods and propose a new method called the homozygote sharing transmission-disequ...

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Detalles Bibliográficos
Autores principales: Chen, Ming-Huei, Cui, Jing, Guo, Chao-Yu, Cupples, L Adrienne, Van Eerdewegh, Paul, Dupuis, Josée, Yang, Qiong
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2367481/
https://www.ncbi.nlm.nih.gov/pubmed/18466536