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Efficiency of multiple imputation to test for association in the presence of missing data

The presence of missing data in association studies is an important problem, particularly with high-density single-nucleotide polymorphism (SNP) maps, because the probability that at least one genotype is missing dramatically increases with the number of markers. A possible strategy is to simply ign...

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Detalles Bibliográficos
Autores principales: Croiseau, Pascal, Bardel, Claire, Génin, Emmanuelle
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2367517/
https://www.ncbi.nlm.nih.gov/pubmed/18466521