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Application of structural equation models to construct genetic networks using differentially expressed genes and single-nucleotide polymorphisms

Understanding the genetic basis of human variation is an important goal of biomedical research. In this study, we used structural equation models (SEMs) to construct genetic networks to model how specific single-nucleotide polymorphisms (SNPs) from two genes known to cause acute myeloid leukemia (AM...

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Detalles Bibliográficos
Autores principales: Lee, Seungmook, Jhun, Mina, Lee, Eun-Kyung, Park, Taesung
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2367521/
https://www.ncbi.nlm.nih.gov/pubmed/18466578