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Genome-wide association mapping using mixed-models: application to GAW15 Problem 3

We apply an analysis based upon mixed-models to the Genetic Analysis Workshop 15, Problem 3 simulated data. Such models are commonly used to mitigate the tendency for population structure, or cryptic relatedness, to inflate the false-positive rate of test statistics. They also allow for explicit mod...

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Detalles Bibliográficos
Autores principales: Zhao, Keyan, Nordborg, Magnus, Marjoram, Paul
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2367554/
https://www.ncbi.nlm.nih.gov/pubmed/18466510