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Incorporating prior biological information in linkage studies increases power and limits multiple testing

We used the Genetic Analysis Workshop 15 Problem 1 data set to search for expression phenotype quantitative trait loci in a highly selected group of genes with a supposedly correlated role in the development of the enteric nervous system. Our strategy was to reduce the level of multiple testing by a...

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Detalles Bibliográficos
Autores principales: Lantieri, Francesca, Rydbeck, Halfdan, Griseri, Paola, Ceccherini, Isabella, Devoto, Marcella
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2367562/
https://www.ncbi.nlm.nih.gov/pubmed/18466592