Cargando…
Incorporating prior biological information in linkage studies increases power and limits multiple testing
We used the Genetic Analysis Workshop 15 Problem 1 data set to search for expression phenotype quantitative trait loci in a highly selected group of genes with a supposedly correlated role in the development of the enteric nervous system. Our strategy was to reduce the level of multiple testing by a...
Autores principales: | Lantieri, Francesca, Rydbeck, Halfdan, Griseri, Paola, Ceccherini, Isabella, Devoto, Marcella |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2367562/ https://www.ncbi.nlm.nih.gov/pubmed/18466592 |
Ejemplares similares
-
Comparative analysis of different approaches for dealing with candidate regions in the context of a genome-wide association study
por: Lantieri, Francesca, et al.
Publicado: (2009) -
Identification of rare variants for hypertension with incorporation of linkage information
por: Chiu, Yen-Feng, et al.
Publicado: (2014) -
Incorporating quantitative variables into linkage analysis using affected sib pairs
por: Chiu, Yen-Feng, et al.
Publicado: (2007) -
Filtering genetic variants and placing informative priors based on putative biological function
por: Friedrichs, Stefanie, et al.
Publicado: (2016) -
Comparison of the power between microsatellite and single-nucleotide polymorphism markers for linkage and linkage disequilibrium mapping of an electrophysiological phenotype
por: Lin, Hsiu-Fen, et al.
Publicado: (2005)