Handling linkage disequilibrium in linkage analysis using dense single-nucleotide polymorphisms

The presence of linkage disequilibrium violates the underlying assumption of linkage equilibrium in most traditional multipoint linkage approaches. Studies have shown that such violation leads to bias in qualitative trait linkage analysis when parental genotypes are unavailable. Appropriate handling...

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Detalles Bibliográficos
Autores principales: Cho, Kelly, Yang, Qiong, Dupuis, Josée
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Proceedings
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2367569/
https://www.ncbi.nlm.nih.gov/pubmed/18466507

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2367569/
https://www.ncbi.nlm.nih.gov/pubmed/18466507

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