Modeling linkage disequilibrium in exact linkage computations: a comparison of first-order Markov approaches and the clustered-markers approach

Recent studies have shown that linkage disequilibrium (LD) between single-nucleotide polymorphism (SNP) markers is widespread. Assuming linkage equilibrium has been shown to cause false positives in linkage studies where parental genotypes are not available. Therefore, linkage analysis methods that...

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Detalles Bibliográficos
Autores principales: Albers, Cornelis A, Kappen, Hilbert J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Proceedings
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2367570/
https://www.ncbi.nlm.nih.gov/pubmed/18466504

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2367570/
https://www.ncbi.nlm.nih.gov/pubmed/18466504

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