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Modeling linkage disequilibrium in exact linkage computations: a comparison of first-order Markov approaches and the clustered-markers approach

Recent studies have shown that linkage disequilibrium (LD) between single-nucleotide polymorphism (SNP) markers is widespread. Assuming linkage equilibrium has been shown to cause false positives in linkage studies where parental genotypes are not available. Therefore, linkage analysis methods that...

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Detalles Bibliográficos
Autores principales:	Albers, Cornelis A, Kappen, Hilbert J
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2007
Materias:	Proceedings
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2367570/ https://www.ncbi.nlm.nih.gov/pubmed/18466504

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