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Dealing with missing phase and missing data in phylogeny-based analysis

We recently described a new method to identify disease susceptibility loci, based on the analysis of the evolutionary relationships between haplotypes of cases and controls. However, haplotypes are often unknown and the problem of phase inference is even more crucial when there are missing data. In...

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Detalles Bibliográficos
Autores principales: Bardel, Claire, Croiseau, Pascal, Génin, Emmanuelle
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2367603/
https://www.ncbi.nlm.nih.gov/pubmed/18466519