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Normalizing a large number of quantitative traits using empirical normal quantile transformation

Variance-components and regression-based methods are frequently used to map quantitative trait loci. The normality of the trait values is usually assumed and violation of this assumption can have a detrimental effect on the power and type I error of such analyses. Various transformations can be used...

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Detalles Bibliográficos
Autores principales: Peng, Bo, Yu, Robert K, DeHoff, Kevin L, Amos, Christopher I
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2367615/
https://www.ncbi.nlm.nih.gov/pubmed/18466501