Dopamine determines the vulnerability of striatal neurons to the N-terminal fragment of mutant huntingtin through the regulation of mitochondrial complex II

In neurodegenerative disorders associated with primary or secondary mitochondrial defects such as Huntington's disease (HD), cells of the striatum are particularly vulnerable to cell death, although the mechanisms by which this cell death is induced are unclear. Dopamine, found in high concentr...

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Detalles Bibliográficos
Autores principales: Benchoua, Alexandra, Trioulier, Yaël, Diguet, Elsa, Malgorn, Carole, Gaillard, Marie-Claude, Dufour, Noelle, Elalouf, Jean-Marc, Krajewski, Stan, Hantraye, Philippe, Déglon, Nicole, Brouillet, Emmanuel
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2367694/
https://www.ncbi.nlm.nih.gov/pubmed/18267960
http://dx.doi.org/10.1093/hmg/ddn033

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2367694/
https://www.ncbi.nlm.nih.gov/pubmed/18267960
http://dx.doi.org/10.1093/hmg/ddn033

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