Age-associated mosaic respiratory chain deficiency causes trans-neuronal degeneration

Heteroplasmic mitochondrial DNA (mtDNA) mutations (mutations present only in a subset of cellular mtDNA copies) arise de novo during the normal ageing process or may be maternally inherited in pedigrees with mitochondrial disease syndromes. A pathogenic mtDNA mutation causes respiratory chain defici...

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Detalles Bibliográficos
Autores principales: Dufour, Eric, Terzioglu, Mügen, Sterky, Fredrik Hansson, Sörensen, Lene, Galter, Dagmar, Olson, Lars, Wilbertz, Johannes, Larsson, Nils-Göran
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2367695/
https://www.ncbi.nlm.nih.gov/pubmed/18245781
http://dx.doi.org/10.1093/hmg/ddn030

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2367695/
https://www.ncbi.nlm.nih.gov/pubmed/18245781
http://dx.doi.org/10.1093/hmg/ddn030

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