Magnitude and direction of DNA bending induced by screw-axis orientation: influence of sequence, mismatches and abasic sites

DNA-bending flexibility is central for its many biological functions. A new bending restraining method for use in molecular mechanics calculations and molecular dynamics simulations was developed. It is based on an average screw rotation axis definition for DNA segments and allows inducing continuou...

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Detalles Bibliográficos
Autores principales: Curuksu, Jeremy, Zakrzewska, Krystyna, Zacharias, Martin
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2367702/
https://www.ncbi.nlm.nih.gov/pubmed/18287117
http://dx.doi.org/10.1093/nar/gkm1135

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2367702/
https://www.ncbi.nlm.nih.gov/pubmed/18287117
http://dx.doi.org/10.1093/nar/gkm1135

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