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Molecular dissection of mRNA poly(A) tail length control in yeast

In eukaryotic cells, newly synthesized mRNAs acquire a poly(A) tail that plays several fundamental roles in export, translation and mRNA decay. In mammals, PABPN1 controls the processivity of polyadenylation and the length of poly(A) tails during de novo synthesis. This regulation is less well-detai...

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Detalles Bibliográficos
Autores principales: Viphakone, Nicolas, Voisinet-Hakil, Florence, Minvielle-Sebastia, Lionel
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2367721/
https://www.ncbi.nlm.nih.gov/pubmed/18304944
http://dx.doi.org/10.1093/nar/gkn080