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Molecular dissection of mRNA poly(A) tail length control in yeast
In eukaryotic cells, newly synthesized mRNAs acquire a poly(A) tail that plays several fundamental roles in export, translation and mRNA decay. In mammals, PABPN1 controls the processivity of polyadenylation and the length of poly(A) tails during de novo synthesis. This regulation is less well-detai...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
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Oxford University Press
2008
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2367721/ https://www.ncbi.nlm.nih.gov/pubmed/18304944 http://dx.doi.org/10.1093/nar/gkn080 |