Generation of ρ(0) cells utilizing a mitochondrially targeted restriction endonuclease and comparative analyses

Eukaryotic cells devoid of mitochondrial DNA (ρ(0) cells) were originally generated under artificial growth conditions utilizing ethidium bromide. The chemical is known to intercalate preferentially with the mitochondrial double-stranded DNA thereby interfering with enzymes of the replication machin...

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Detalles Bibliográficos
Autores principales: Kukat, Alexandra, Kukat, Christian, Brocher, Jan, Schäfer, Ingo, Krohne, Georg, Trounce, Ian A., Villani, Gaetano, Seibel, Peter
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2367725/
https://www.ncbi.nlm.nih.gov/pubmed/18353857
http://dx.doi.org/10.1093/nar/gkn124

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2367725/
https://www.ncbi.nlm.nih.gov/pubmed/18353857
http://dx.doi.org/10.1093/nar/gkn124

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