Solution structure of a let-7 miRNA:lin-41 mRNA complex from C. elegans

let-7 microRNA (miRNA) regulates heterochronic genes in developmental timing of the nematode Caenorhabditis elegans. Binding of miRNA to messenger RNA (mRNA) and structural features of the complex are crucial for gene silencing. We herein present the NMR solution structure of a model mimicking the i...

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Detalles Bibliográficos
Autores principales: Cevec, Mirko, Thibaudeau, Christophe, Plavec, Janez
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2367737/
https://www.ncbi.nlm.nih.gov/pubmed/18296482
http://dx.doi.org/10.1093/nar/gkn088

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2367737/
https://www.ncbi.nlm.nih.gov/pubmed/18296482
http://dx.doi.org/10.1093/nar/gkn088

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